When 4 American tourists – Sofia, Carl, Belle and Michael – go on a ghost tour, they get much more than they bargained for, when the ghosts of an evil Doctor and his last patient victim trap them in the old abandoned psychiatric ward.
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After being murdered by corrupt colleagues in a covert government agency, Al Simmons (Michael Jai White) makes a pact with the devil to be resurrected to see his beloved wife Wanda (Theresa Randle). In exchange for his return to Earth, Simmons agrees to lead Hell’s Army in the destruction of mankind.
When two troublemaking female prisoners (one a revolutionary, the other a former harem-girl) can’t seem to get along, they are chained together and extradited for safekeeping. The women, still chained together, stumble, stab, and cat-fight their way across the wilderness, igniting a bloody shootout between gangsters and a group of revolutionaries.