A man recovering from a nervous breakdown and the recent death of his mother begins to believe another entity is living within the walls of his home.
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Caroline, a woman in her late thirties, has lost everything and is searching for a new beginning. She moves into an old apartment and starts to realize that she is not as alone as she thought she was. Just as she is searching for something new, something old is searching for her.
A young man is confined in a mental hospital. Through a flashback we see that he was traumatized as a child, when he and his family were circus performers: he saw his father cut off the arms of his mother, a religious fanatic and leader of the heretical church of Santa Sangre (“Holy Blood”), and then commit suicide. Back in the present, he escapes and rejoins his surviving and armless mother.
Two investigators of paranormal hoaxes, the veteran Dr. Margaret Matheson and her young assistant, Tom Buckley, study the most varied metaphysical phenomena with the aim of proving their fraudulent origins. Simon Silver, a legendary blind psychic, reappears after an enigmatic absence of 30 years to become the greatest international challenge to both orthodox science and professional sceptics. Tom starts to develop an intense obsession with Silver, whose magnetism becomes stronger with each new manifestation of inexplicable events. As Tom gets closer to Silver, tension mounts, and his worldview is threatened to its core.
The story follows a family of inbreeds that have been afflicted by a genetic disorder known as ‘Merrye syndrome’, named after the family in which the disorder developed. This malady causes it’s victims to enter a state of age regression that starts at the age of ten and continues throughout the remainder of the person’s life, rendering them with the intelligence of a child. The final generation of the family has been entrusted to the care of the family chauffeur (Lon Chaney Jnr), and all is well for these odd people until a greedy branch of the family decides that they want to relieve the family of it’s home. Mental illness has always, and will always be, a fascinating subject for horror movies as it probes into the unknown and Spider Baby makes best use of that fact.
On a future earth where 98% of the surface is underwater, a Warlord who controls an army of sharks meets his match when he captures the daughter of a mysterious shark caller who must learn to marshal a supernatural ability if she is to free her people from the Warlord’s dominion.